relationship between clinicobiochemical markers and depression in women with polycystic ovary syndrome

Previous studies have demonstrated that clinical features of 16TPolycystic ovary syndrome16T [PCOS] are associated with a lower degree of health, self, and sex satisfaction. Our study aimed to investigate possible associations between depression and different clinicobiochemical markers of PCOS. In a cross-sectional analytic study, 120 PCOS women aged 18-45 yr, were enrolled. Beck Depression Inventory was used to assess depression. Also, all participants underwent biochemical studies. Individuals with 15 points and more in Beck test were referred to a psychiatrist to participate in a complementary interview for the diagnosis of depression based on Diagnostic and Statistical Manual of Mental Disorders IV [DSMIV-TR] criteria. Among the study participants, 82 women [68.3%] were non-depressed, and 38 patients [31.7%] had some degrees of depression. According to the psychiatric interview, 10 patients [8.3%] had major depression, 22 patients [18.3%] had minor depression and 6 patients [5%] had dysthymia. We failed to show any significant difference in body mass index, hirsutism, infertility, serum total testosterone, lipid profile, and the homeostasis model assessment of insulin resistance [HOMA-IR] between depressed and non-depressed subjects [p>0.05]. Using Spearman correlation, we did not find a positive correlation between BDI scores and clinicobiochemical markers for all PCOS subjects [-0.139 0.05]. In spite of high rate of depression in women with PCOS, there was no significant association between Clinicobiochemical Markers and depression

Comparison of gestational diabetes mellitus and pre-eclampsia in women with high hemoglobin in the first trimester of pregnancy: a longitudinal study

To determine the association between high hemoglobin with gestational diabetes mellitus [GDM] and preeclampsia in pregnant women in the first trimester. This cohort study was conducted among 973 pregnant women who started their antenatal booking in the first trimester [first 14 weeks of gestation]. Women with first-visit high Hb levels [> 12.5 g/L] on first visit of the pregnancy period were selected as the study group and were compared with those who had normal Hb value [< 12.5 g/L] as controls. Adverse pregnancy outcomes including preeclampsia and GDM were compared between the two groups. Complete obstetric records of 448 women with high Hb levels and 486 women with normal Hb levels were studied. The follow up showed that the women with high Hb levels had significantly higher rates of preeclampsia and GDM than those with normal Hb levels; the risks were 5.4 [95% cl; 2.8 to 10.5] and 3.7 [95%cl; 2.2 to 6.4], respectively. This study found that high Hb in the first trimester is associated with higher risk of subsequent preeclampsia and gestational diabetes mellitus [GDM]

Suicide and associated risk factors in Hamadan province, west of Iran, in 2008 and 2009

Hamadan is a province with high incidence rate of suicide. The present study was conducted to assess suicide and its associated risk factors in this province. In this cross-sectional study, all cases of suicide occurred in the province, were investigated from April 2008 to March 2010. The data were collected from Provincial Health Center and Forensic Medicine's databases using a checklist developed according to the available records. A number of 5414 suicide attempts had occurred [with 8.4% deaths] including 2753 women [with 3.4% death] and 2660 men [with 13.7% death]. Majority of the suicide attempts and com-pleted suicides occurred among adults aged 20-29 years. About 6.7% of the cases who attempted for suicide and 14.2% of the cases who died from suicide had a previous history of suicide attempt [P<0.001]. Familial problems [49.7%] and psychiatric disorders [31.6%] were among the most common reasons of suicide attempt. Using drugs [74.0%] were the most common method of attempting suicide while hanging [83.6%], burning [74.2%], and gunshot [52.4%] were the most common leading causes of completed suicide [P<0.001]. Adjusted odds ratio estimate of completed suicide in males against females was 2.27 [95% CI: 1.63, 3.14]. The odds of completed suicide increased 1.43 [95% CI: 1.30, 1.57] fold per 10 years of age. This survey identified and highlighted the most common and important potential risk factors for suicide. In addition, the effects of various demographic risk factors on suicide attempt and completed suicide were examined. These evidences may be useful for future research, policy, and treatment efforts aimed at understanding and preventing suicide.